Debuting in 1990, "The Simsons" is both the longest running sitcom and the longest running animated show in America. And throughout its extensive run, it has never failed to satirize the world we live in, along with creating bizarre new scenarios that we may have never thought could actually happen. Well, I've got news for you, a lot of those ridiculous jokes from the show actually did occur in the real world after the episodes aired!

Tomacco
Tomacco
In one memorable episode, Homer and the family move onto a farm and he begins planting crops. With the help of some radioactive waste, Homer winds up growing a tomato/tobacco hybrid plant that everyone goes crazy over.
The Real Tomacco
The Real Tomacco
An Oregon scientist named Rob Baur got inspired by Homer's discovery, and set out to create his own tomacco crop. From grafting together a tobacco root and a tomato plant, he succeeded in creating the hybird. It looked just like a tomato, but contained nicotine.
Flaming Moe
Flaming Moe
Springfield's local tavern owner had an uncharacteristically lucky claim to fame after he stole the idea for a new drink from Homer. The Flaming Moe is a cocktail that includes cough medicine and is set on fire when served.
The Real Flaming Moe
The Real Flaming Moe
New York bar owner Andy Heidel overheard some of his patrons talking about Flaming Moes, and noticed that he actually had a bottle of Robitussin behind the bar. He mixed it with Pernod, Jagermeister, and Bacardi 151, set it on fire, and served an actual Flaming Moe.
Flanders' Leftorium
Flanders' Leftorium
Ned Flanders, the Simpsons' hyper positive, bible-thumping neighbor, gets the idea to open a store selling only left-handed products in one episode. Flanders himself is left-handed, and although the Leftorium originally fails, it becomes a moderate success in the show.
Lefty's
Lefty's
Flanders' idea reached the real world in 2009, when Lefty's opened its doors in San Francisco. Selling everything from left-handed office supplies to shirts and mugs with left-handed saying printed on them, the store became a success and opened a second location at Walt Disney World Resorts in Florida.
Itchy & Scratchy's Bloody Billboard
Itchy & Scratchy's Bloody Billboard
Within the universe of "The Simpsons," "Itchy & Scratchy" represent extreme cases of cartoon violence. When the cat and mouse show premiered a movie, it utilized a giant billboard that sprayed blood periodically.
Real Bloody Billboard
Real Bloody Billboard
New Zealand apparently didn't see anything wrong with this blood-flooding type of advertising, and decided to replicate it to advertise the TV premiere of "Kill Bill." Splattered red paint covers the walls, sidewalk, and even a few cars near the billboard.
Grease Is The Word
Grease Is The Word
In one episode, Homer hatches the plan to take used grease from the back of the elementary school's kitchen and sell it for a profit. He eventually has to give up the act, but makes a pretty penny first.
Real Grease Burglars
Real Grease Burglars
Although the concept of the episode seemed ridiculous, it actually predicted (or maybe just exposed) a pretty bothersome criminal activity in the restaurant industry. A 2011 story in the St. Louis Post Dispatch reported a recent wave of grease stealing from a local wings restaurant, and the owner spoke about a large underground market for used cooking grease.
Viva Ned Flanders
Viva Ned Flanders
The episode "Viva Ned Flanders," Homer takes Ned on a road trip to Las Vegas to show him how to let loose and have some fun. The two of them get very drunk, and wake up in their casino hotel married to two cocktail waitresses. They run away but are stopped by a crowd of people, including a tiger and heavyweight boxer Drederick Tatum (who is based on Mike Tyson).
The Hangover
The Hangover
Chances are that description sounded a bit familiar to you. It very closely resembles the plot of "The Hangover," which came out 10 years later in 2009. Both stories feature characters waking up drunk without recollection of major events in a casino hotel room, both include characters marrying random women without remembering it, both have a tiger, and both have Mike Tyson (or a Tyson-inspired character in the case of "The Simpsons").
Lunch Lady Doris' Gym Mat Meat
Lunch Lady Doris' Gym Mat Meat
One episode of "The Simpsons" shows Lunch Lady Doris running gym mats through a meat grinder. Apparently, this is what she is serving the kids for their school lunches.
McDonalds' Gym Mat Sandwich
McDonalds' Gym Mat Sandwich
Like Lunch Lady Doris, McDonalds seemed to like the idea of using gym mats in their food. One of the ingredients found in the bun of the McRib is Azodicarbonamide, which is most commonly used in the production of gym mats to keep them spongey. The substance, which is banned in Europe, can also be found in some breads at Subway.
Schwarzenegger's Leadership
Schwarzenegger's Leadership
In "The Simpson's Movie," Governor Schwarzenegger is now President Schwarzenegger. When he is presented with a stack of papers to go through, he responds by saying "I was elected to lead, not read."
Cain's Leadership
Cain's Leadership
Taking this sentiment seriously, in the 2012 elections, politician Herman Cain ran for president with the slogan "We need a leader, not a reader." Thankfully, the American public was smart enough to realize just what a terrible slogan that was.
Homer's Land Of Chocolate
Homer's Land Of Chocolate
When German businessmen are preparing to purchase Springfield, they explain their country of origin to Homer by calling it "the land of chocolate." Of course, Homer immediately imagines himself in a town made entirely of chocolate, complete with chocolate dogs and rabbits running around.
China's Land Of Chocolate
China's Land Of Chocolate
Fulfilling all of Homer's fantasies, Shanghai recently opened a theme park that is entirely made from chocolate. The park contains over 80 tons of Belgian chocolate that is expertly sculpted into famous Chinese attractions, including the Terracotta warriors and the Great Wall.
McBain's Icy Pun
McBain's Icy Pun
Several episodes of "The Simpsons" feature the characters watching movies that star the action star McBain, who is very obviously based on Arnold Schwarzenegger.  In one of these movies, McBain bursts out of an ice sculpture and quips "Ice to see you" before shooting everyone in the room.
Schwarzenegger's Icy Role
Schwarzenegger's Icy Role
In 1997, McBain's inspiration, Arnold Schwarzenegger was in the movie "Batman & Robin," playing the villain Mr. Freeze. Of course, this role included a blizzard of ice-related puns on par with McBain's "Ice to see you again."
Scotchtoberfest
Scotchtoberfest
In his never-ending attempts to discipline Bart, Principal Skinner sets up a Scottish pride event known as Scotchtoberfest. Skinner knows Bart won't be able to resist pranking Groundskeeper Willie, and hopes to catch him in the act at the event.
The Real Scotchtoberfest
The Real Scotchtoberfest
Vintage Wine & Spirits Co. in Des Moines, Iowa decided that they wanted a way to celebrate the Scottish heritage of Iowa. Unlike Skinner, they set up their annual Scotchtoberfest, which occurs every Saturday in October, to be an event full of food, drink, and fun!
Sarcasm Detector
Sarcasm Detector
When Professor Frink pulled out a sarcasm detector to monitor Lisa's speech patterns, viewers saw the machine as a clever joke.
Real Sarcasm Detector
Real Sarcasm Detector
In actuality, though, the Secret Service is working on making one! The security agency is in the works to create a device that can scan social media to find threats against the President, and be able to filter out any sarcasm.
Not All You Can Eat
Not All You Can Eat
In one episode, Homer is elated to try out a new all-you-can-eat seafood buffet in Springfield. Of course, Homer makes the most of the experience, and is actually kicked out of the restaurant for eating too much.
Really Kicked Out
Really Kicked Out
Will Wisth had the same excitement as Homer did when he entered an all-you-can-eat fish fry in Wisconsin. But after eating 12 fish fillets, he was asked to leave the restaurant.
Crime Is Sweet
Crime Is Sweet
In one episode, Homer steals a huge pile of sugar from a crashed truck and keeps it in his back yard. He plans to sell it door to door, but the sugar melts in the rain.
A Real Sugar Heist
A Real Sugar Heist
Two boys in India actually stole a sugar truck in 2009. They were supposed to clean the truck, but took it while it was parked at their boss's house.
Up, Up, And Buffet
Up, Up, And Buffet
Back in 1998, it seemed farfetched for the Simpsons to dine at an airplane restaurant. That's exactly what they did, though, int their ninth season finale.
Real Airplane Restaurant
Real Airplane Restaurant
Now, anyone can eat at an airplane restaurant. An old Air Force plane has been converted into a restaurant in Colorado Springs.
The Original Octomom
The Original Octomom
Before having 8 babies at once was an actual thing, it was an exaggeration of Kwik-E-Mart owner Apu's overexertion. When his wife Manjula gave birth to octuplets after using too many fertility drugs, nobody believed that it would happen anywhere except a cartoon.
The Real Octomom
The Real Octomom
In 2009, Nadya Suleman shocked the nation by giving birth to octuplets. Suleman instantly became a celebrity, going on various talk shows, gracing the cover of many magazines, and even getting some reality show offers.

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